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PP

Software Engineer

Praxis Precision Medicines, Inc.

105,000 - 125,000 / year

United States - RemoteInternRemoteIntermediate

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Description

Location:  This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

The Opportunity
Praxis Precision Medicines is building a strong pipeline of Software Engineering talent to support the continued evolution of our eDiary and clinical data platforms. Engineers in this role will first contribute to and grow within our eDiary ecosystem—a regulated, patient-facing platform used across our Epilepsy portfolio. Our engineers work across modern web and mobile applications, secure clinical data platforms, cloud infrastructure, distributed system architectures, API design, auditability frameworks, identity and access control systems, and production observability. When you apply to this position, your profile will be considered for current and future Software Engineer openings supporting the eDiary platform and adjacent clinical systems. 

Primary Responsibilities

  • Design, develop, and maintain reliable, production-grade code across frontend, backend, and data layers, implementing software solutions that meet clinical, operational, and regulatory requirements 
  • Deploy and operate services in a cloud environment (AWS preferred) and contribute to architecture and design reviews with a focus on reliability, scalability, and security 
  • Debug and resolve production issues across distributed and asynchronous workflows; diagnose performance bottlenecks; and own incident response, including root cause analysis and durable fixes that prevent recurrence 
  • Collaborate with QA, Clinical Operations, Clinical Development, Product, and IT stakeholders to translate requirements into validated releases 
  • Design APIs and data models that preserve audit trails, version history, and system traceability; and improve system observability through structured logging, monitoring, and alerting 
  • Uphold high standards for data integrity, security, and regulatory compliance across all systems 

Qualifications and Key Success Factors

  • Bachelor’s degree in Software Engineering or equivalent practical experience 
  • 3+ years of non-internship professional software development experience, with demonstrated ability to design, build, and operate production software systems end-to-end 
  • Demonstrated experience using AI-assisted development tools (e.g., code generation, automated testing, debugging copilots) to improve engineering productivity and code quality, with ability to critically evaluate AI-generated outputs for correctness, security, and maintainability 
  • Strong foundation in software engineering fundamentals: data structures and algorithms, API and interface design, relational data modeling and transactional integrity, and separation of concerns 
  • Demonstrated ability to debug complex issues across multiple layers (client, API, database, infrastructure) and trace issues in distributed or asynchronous systems using logs, metrics, and instrumentation 
  • Experience deploying and operating applications in a cloud environment (any major provider), including networking, access control, configuration, and monitoring; and experience designing secure systems including authentication and authorization flows 
  • Experience implementing production-grade monitoring, alerting, and CI/CD practices; and ability to work effectively in a remote-first, high-accountability environment 
  • The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement.  You’ll need comfort with screen work, basic hand coordination, and focus.  Reasonable accommodations may be made to enable individuals with disabilities to perform these functions. 
Annualized Base Salary
$105,000—$125,000 USD

Compensation & Benefits

At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive.  This includes 99% of the premium paid for medical, dental and vision plans.  We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future?  We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP.  We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns.  Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring.  We aim high, collaborate hard, and produce results.  Let’s achieve the impossible together! 

Company Overview
 

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance.  At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders.  Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.

Diversity, Equity & Inclusion
Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.

Attention: Job Scam Alert
Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com.

Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.

Benefits

  • health insurance
  • 401(k)
  • paid time off
  • stock options
  • life insurance

About this role

Praxis Precision Medicines is seeking a Software Engineer to help build and maintain its eDiary platform—a regulated, patient-facing system used across its Epilepsy portfolio. This is a remote position with travel flexibility as needed, and you'll work across the full stack: frontend and mobile applications, backend services, cloud infrastructure, and the data systems that support clinical workflows. The role spans design and development of production-grade code, cloud deployment and operations on AWS, debugging distributed systems, and collaborating with clinical, product, and QA teams to translate requirements into validated releases.

The ideal candidate has at least three years of professional software development experience and a strong foundation in fundamentals: data structures, API design, relational databases, and debugging across multiple layers. You'll need hands-on experience deploying and operating applications in a cloud environment, designing secure systems with proper authentication and authorization, and implementing monitoring and CI/CD practices. Comfort with AI-assisted development tools and the ability to critically evaluate their outputs is expected. Because this work touches regulated clinical systems, you must be detail-oriented about data integrity, security, and compliance.

This role is structured as an internship with a salary range of $105,000–$125,000 and includes comprehensive benefits: medical, dental, and vision coverage with 99% premium paid by the company, 401(k) matching up to 6%, stock incentives, discretionary quarterly bonuses, flexible wellness benefits, and generous PTO. It suits someone ready to own production systems end-to-end in a remote-first, high-accountability environment.

Typical pay for this role

$140,000

Typical range: $120,000 to $140,000

Pay for this role

$105,000 to $125,000 per year

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