Bio-Analytical Co-op-Northeastern Students
Seaport Therapeutics
Salary undisclosed
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Description
Seaport Therapeutics is a clinical-stage therapeutics company advancing the development of novel neuropsychiatric medicines in areas of high unmet patient needs. The Company has a proven strategy of advancing clinically validated mechanisms previously held back by limitations that are overcome with its proprietary GlyphTM technology platform. All the therapeutic candidates in its pipeline of first and best-in-class medicines are based on the Glyph platform, which is uniquely designed to enable oral bioavailability, bypass first-pass metabolism and reduce hepatotoxicity and other side effects. Seaport is led by an experienced team that invented and advanced important neuropsychiatric medicines and are guided by an extensive network of renowned scientists, clinicians and key opinion leaders. For more information, please visit www.seaporttx.com.
Job Description
Seaport Therapeutics is seeking a co-op student for a lab-based bioanalysis position to be part of our Discovery team. This co-op will have a focus on LC-MS to assist in the screening of novel drugs. We are looking for a highly motivated individual who is looking to be a part of a multidisciplinary team and to gain experience in a startup environment. This position will contribute to advancing the pipeline of impactful candidates generated from our novel Glyph™ prodrug platform.
Some of the responsibilities will include:
- Executing in vitro experiments, using LC-MS, for the screening of lipid prodrugs to support preclinical discovery
- Processing and analyzing in vivo samples (plasma, lymph fluid, etc.) to generate DMPK data for various prodrugs
- Contributing to the development and optimization of LC-MS methods for both quantitative and qualitative analysis
- Routine use and troubleshooting of LC-MS instrumentation
- Documenting all experiments using an electronic notebook and analyzing data for reports and regular internal presentations
Experience and Skills
- Enrolled in a Chemistry, Biochemistry, Pharmaceutical Sciences, Chemical Engineering, or related program at the Master’s Level
- Previous Co-op or lab experience is preferred
- Knowledge of or experience with: HPLC, reverse phase chromatography, mass spectrometry instrumentation, enzyme kinetics, protein precipitation, liquid-liquid extraction
- Strong organizational skills, attention to detail, and eagerness to learn.
About this role
Seaport Therapeutics is looking for a co-op student to join its Discovery team in a hands-on bioanalysis role centered on LC-MS work. You would support the screening and characterization of novel neuropsychiatric drug candidates built on the company's proprietary Glyph platform, executing in vitro experiments, processing in vivo samples for DMPK analysis, and contributing to the development and optimization of LC-MS methods. The work involves routine instrument operation and troubleshooting, data analysis, and documentation via electronic notebook.
This position suits someone enrolled at the Master's level in Chemistry, Biochemistry, Pharmaceutical Sciences, Chemical Engineering, or a related field who has prior co-op or lab experience and familiarity with HPLC, reverse-phase chromatography, mass spectrometry, enzyme kinetics, and sample preparation techniques like protein precipitation and liquid-liquid extraction. You'll need strong organizational skills, attention to detail, and genuine interest in learning within a startup environment. The role is based in Boston and requires in-office work.
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