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Research Associate II - Ingredient and Product Innovation

Debut Biotech

$70,000 - $85,000 / year

San Diego, CAOn-siteNovice

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Description

About Debut

Debut is the unconventional innovation lab spearheading the next generation of big business. Only Debut has a scalable, integrated, climate-positive creation model powered by biotechnology that puts human wellbeing at the center of everything we do—setting the new standard for profitable business and a new pace for an ever-changing world.  Our hybrid biotechnology approaches unlock latent markets, providing access to sustainably produced, natural ingredients with health benefits that cannot be obtained through other methods. We are committed to traversing the entire process, from ingredient discovery to the scaling of these products, for consumer markets. If you are passionate, enjoy fast-paced innovation and collaborative teams, then Debut is for you.  

Research Associate II - Ingredient and Product Innovation

 

Summary

Debut is seeking a Research Associate II to support the development and execution of in vitro assays for skincare ingredient discovery. The successful candidate will design and execute cell-based assays, maintain mammalian cell banks, and generate high-quality data in support of discovery programs.

 

Essential Functions

  • Perform routine maintenance and expansion of mammalian cell lines.
  • Execute, optimize, and troubleshoot in vitro cell-based assays utilizing techniques such as plate-based assays (e.g., absorbance, luminescence, fluorescence readouts), ELISA, flow cytometry, qPCR, and colorimetric assays.
  • Perform isolation, purification, and characterization of nucleic acids to support gene expression analyses.
  • Execute high-throughput sample processing workflows.
  • Ensure sterile handling of samples, reagents, and laboratory equipment.
  • Contribute to new assay design, development, and validation.
  • Conduct thorough literature reviews and contribute to experimental planning based on peer-reviewed research.
  • Collect, analyze, and interpret experimental data while maintaining accurate records in electronic lab notebooks and databases.

 

Education and Experience

  • Bachelor’s degree + 2 years of experience OR Associate’s degree + 4 years of experience in cell biology, molecular biology, or a relevant field.
  • Demonstrated experience in mammalian cell culture.
  • Experience performing in vitro assays using standard cell biology techniques.
  • Industry experience for mammalian cell culture is a plus.
  • Experience with coding and automated record keeping is a plus.

 

Essential Physical Characteristics

The physical characteristics described here are representative of those that must be met by an employee to successfully perform the essential functions of this position. Reasonable accommodations may be made to enable qualified individuals with disabilities to perform the essential functions of a job, on a case-by-case basis. 

  • Continuous upward and downward flexion of the neck. 
  • Frequent: sitting, repetitive use of hands to operate computers, printers and copiers. 
  • Frequently uses hands to feel objects or control tools (e.g. pipetting).  Laboratory operations require dexterity and care to perform studies as required.
  • Occasional: walking, standing, climbing stairs, bending and twisting of neck, bending and twisting of waist, squatting, simple grasping, reaching above and below shoulder level, and occasional lifting and carrying of files or material weighing up to 50 pounds.
  • Must be willing to work with biohazardous agents (up to BSL2).
  • The R&D laboratory will result in exposure to hot and cold temperatures, noise, fumes, limited dust, and oily coolants. 
  • The performance of this position will present exposure to an industrial environment and requires support and compliance with the published Company PPE policy including but not limited to the use of personal protective equipment such as safety glasses with side shields, appropriate attire, safety shoes, hard hat, hearing protection, etc. 

Condition of Employment

As part of Debut’s pre-employment process, prospective candidates will undergo a background check prior to beginning employment. Additional types of background investigations may be conducted based on the job-related activities of the position.

Debut is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.

 

Salary: $70,000 - $85,000

 

 

About this role

Debut Biotech is looking for a Research Associate II to drive ingredient discovery for skincare products using cell-based assays and mammalian cell culture techniques. You'd own the day-to-day lab work—maintaining cell lines, designing and executing in vitro assays (plate-based readouts, ELISA, flow cytometry, qPCR), processing samples at scale, and generating the experimental data that feeds the company's discovery pipeline. The role also involves literature review, assay validation, data analysis, and meticulous record-keeping to support the team's innovation efforts.

You'll need a bachelor's degree plus two years of hands-on cell biology or molecular biology experience, or an associate's degree plus four years in a related field. Direct experience with mammalian cell culture and standard in vitro assay techniques is required; industry background, coding skills, and familiarity with automated record-keeping systems are valued additions. This is a full-time, in-office position in San Diego with a salary range of $70,000 to $85,000. The work involves routine lab hazards—biohazardous agents up to BSL2, temperature and chemical exposure—and requires comfort with pipetting, fine motor control, and standard laboratory PPE.

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Pay for this role

$70,000 to $85,000 per year

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