Senior Manager, Commercial Supply Chain Serialization & Traceability

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.

As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity We are seeking an experienced Senior Manager, Commercial Supply Chain, Serialization & Traceability to lead global serialization and traceability capabilities supporting commercial product launches and lifecycle management activities. This role is responsible for supporting compliant and scalable serialization operations across global supply networks, including CMOs, packaging sites, wholesalers, 3PLs, and external service providers.

The ideal candidate will bring hands-on experience supporting or leading global serialization implementations, including EU FMD operational readiness, EPCIS data exchange, aggregation, and downstream trading partner connectivity. This role partners cross-functionally with Supply Chain, Quality, Regulatory, Packaging, Manufacturing, and IT teams to ensure compliant execution of global traceability

Requirements

, including DSCSA, EU FMD, and emerging international regulations.

, including DSCSA, EU FMD, and emerging international regulations. Support management, investigation, escalation, and resolution of EU FMD alerts in coordination with internal stakeholders, CMOs, EMVO-connected partners, and external service providers. Maintain and support global GS1 registration activities, including management of company prefixes, GTIN structures, GLNs, and associated product identification data supporting serialization and traceability operations.

Maintain oversight of serialized product onboarding, aggregation strategies, and downstream trading partner readiness activities. Serve as a subject matter expert for serialization operations, EPCIS data exchange, and global traceability

Approve serialized commercial artwork, labeling implementation, and packaging change management activities. Serialized Data Governance & Partner Management Oversee serialized data exchange processes among CMOs, packaging sites, logistics providers, wholesalers, and external trading partners. Support investigation and resolution of serialization data exchange issues, failed transmissions, aggregation discrepancies, and connectivity exceptions.

Support operational metrics and dashboards related to serialization health, partner readiness, and data integrity. Partner with CMOs, 3PLs, wholesalers, and serialization service providers to ensure operational readiness and ongoing compliance. Compliance, Documentation, & Cross-Functional Leadership Author and maintain serialization and traceability SOPs, work instructions, business processes, and associated documentation.

Maintain serialization and traceability procedures, work instructions, and business process documentation. Own change controls and risk assessments and support audits, inspections, investigations, CAPAs, associated with serialization processes and systems. Serve as a central coordination point between Supply Chain, Quality, Regulatory, Packaging, Manufacturing, and IT teams for serialization and traceability initi

Key Responsibilities

Serialization & Traceability Operations Lead serialization and traceability operational readiness activities supporting commercial launches and ongoing supply operations. Support implementation and operationalization of global serialization and traceability