Director, Regional Site Liaison

About Jade Biosciences Jade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases. Jade’s lead candidate, JADE101, targets the cytokine APRIL, and is currently being evaluated in a Phase 1 clinical trial for the treatment of immunoglobulin A nephropathy. Jade’s pipeline also includes JADE201, an afucosylated anti-BAFF-R monoclonal antibody, as well as JADE301, an undisclosed antibody candidate, both currently in preclinical development.

Jade was launched based on assets licensed from Paragon Therapeutics, an antibody discovery engine founded by Fairmount. com and follow the Company on LinkedIn . Role Overview Reporting to the E xecutive D irector of Clinical Partnerships & Engagement, the Regional Site L iaison ( RS L) is a field-based operational and scientific partner who serves as a critical link between Jade and clinical trial sites.

This role is responsible for local clinical leadership and accountability, and will driv e site engagement, ensure consistency in trial execution, and leverage regional insights to ensure successful clinical trial enrollment.

Key Responsibilities

Build and maintain strong relationships with Principal Investigators (PIs), site staff and KOLs in support of planned and active clinical trials. Organize and execute in-person visits with PIs and site teams. Serve as the Jade primary point of contact for regionally assigned clinical trial sites across one or more programs: Provide protocol support to Investigators and site teams.

Support and reinforce site accountability of enrollment targets. Respond promptly to site inquiries outside of CRA scope, with appropriate cross-functional escalation as needed. Identify and resolve site challenges efficiently, delivering a high level of service.

Partner with internal teams and CRO to develop and execute tailored site engagement strategies. Gather and communicate field insights to internal Jade team, including performance metrics and other KPIs, protocol feedback, and competitive trial activity. Provide regular updates to Clinical Operations on site-level enrollment plans and performance to support global enrollment strategy and consistent trial execution.

Maintain alignment with Clinical Operations, Clinical Development, Medical Affairs, and CRO partners (including CRAs). Support site initiation, activation and ongoing trial conduct as requested by Clinical Operations, including co-monitor with CRA where appropriate.

Qualifications

Bachelor's degree in a related field required; advanced scientific or clinical degree is preferred. g. CRA, MSL, CTM).

Strong understanding of clinical trial protocols, processes, and compliant, non-promotional scientific exchange. Knowledge of FDA and ICH Guidelines, GCP, and clinical research standards. Excellent interpersonal and communication skills, with the ability to build effective relationships with internal and external stakeholders, including CROs.

Demonstrated problem-solving skills and ability to escalate issues appropriately. Ability to work independently in a field-based role. Proven ability to operate effectively in a dynamic and fast-paced environment.

Willingness to travel domestically or regionally (~ 50%). International travel may be required as needed to support global programs. Position Location This is a remote role; periodic travel to team and company events is required.

The anticipated salary range for candidates for this role is $170,000 - $190,000 at the Associate Director level and $210,000 - $235,000 at the Director level.