Senior Scientist I/II, Bioprocess Development

COMPANY DESCRIPTION Flagship Pioneering is a bioplatform innovation company that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health, sustainability and beyond exponentially accelerate scientific progress in areas ranging from disease detection and treatment and nature-positive agriculture to novel applications of AI that are driving the creation of new technologies.

What sets Flagship apart is our ability to advance science and technology by uniting innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. THE ROLE We are seeking a Senior Scientist I/II, bioprocess development and microbial production subject matter expert and in-lab technical lead for a high impact, novel biological platform. This role will focus primarily on fermentation process development, translating early-stage biological systems into scalable and manufacturable processes.

The successful candidate will work collaboratively at the interface between microbial engineering and bioprocess optimization.

KEY RESPONSIBILITIES

Design, execute, and iterate on bioprocess experiments to support scalable fermentation process development including collaboration with Strain Development on strain improvements to support bioprocess productivity and robustness, media development, feeding design, mass transfer optimization, and process control Translate biological discoveries into robust production systems by improving yield, productivity, and process reproducibility Contribute to implementation and buildout of experimental frameworks for systematic process improvement, including DOE-based optimization and fermentation analytics Execute technology transfer to external CROs, CMOs, or manufacturing partners as subject matter expert as needed PROFESSIONAL EXPERIENCE

QUALIFICATIONS

PhD in biochemical engineering, microbiology, chemical engineering, or a related discipline Scientist I: At least 5-7 years of professional experience, including 1+ years hands-on developing microbial fermentation processes in an industrial or translational setting Scientist II: At least 8-11 years of professional experience, including 3+ years hands-on developing microbial fermentation processes in an industrial or translational setting Demonstrated expertise in fermentation process development scale-up, including optimizing parameters such as oxygen transfer, feeding regimes, media composition, etc.