Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.

As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Director, Global Business Systems Enablement is responsible for defining, establishing, and evolving the operating model that enables Commercial, Medical Affairs, and selected G A global business systems across markets outside the United States. This role ensures that regional needs are clearly understood, refined, and effectively integrated into scalable global processes and governance, including launch orchestration, compliance frameworks, software development lifecycle practices, prioritization, and demand management.

Working in close partnership with regional IT leaders, global Commercial and Medical solution teams, G A Systems, and enterprise technology partners, this leader establishes, drives, and continuously improves the governance, planning, and execution models required to support an expanding global business while ensuring business demand is effectively qualified, prioritized, and delivered through those processes. For new market launches outside the United States, this individual leads the associated Go-to-Market and selected G A business systems workstreams, ensuring coordinated planning, readiness, and execution across regional IT teams, global Commercial and Medical solution teams, and enterprise technology teams.

Requirements

, identifying cross-market commonalities, and reducing discovery work for global delivery teams such as Omnichannel Solutions, Data Solutions, Medical Affairs Solutions, and Field Solutions. The role strengthens the frameworks, governance, and ways of working that enable seamless pull through of work into global intake and execution models while helping regional IT leads and enterprise partners operate more efficiently and maintain alignment with global standards. Partnering closely with IT, Information Security, Planning Management, G A Systems, R D Systems, and other enterprise technology partners, this leader influences strategic planning and business transformation initiatives while continuously evolving the operating model and cross-functional partnerships to strengthen coordination, improve visibility, and ensure scalable, compliant, and launch-ready execution without creating bottlenecks or slowing direct collaboration where it is most effective.

The Director also brings a forward-looking perspective on AI, analytics, automation and digital innovation, identifying practical opportunities to improve decision-making, simplify ways of working, and strengthen global business capabilities. Global Enablement and Orchestration Lead the Go-to-Market and selected G A business systems workstream for Global Markets (outside of the United States), providing strategic leadership, governance, coordination, and visibility across regional initiatives. Lead engagement between regional IT organizations in Europe and Japan and the global Commercial, Medical, and G A Information Systems team, while fostering strong partnership with enterprise IT.

For global systems, translate regional business needs into executable work in partnership with global solution teams. Drive effective qualification and prioritization of ex US demand before it enters global intake forums.