Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.

Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma. Legend Biotech is seeking a Head, Business Operations and Alliance Management as part of the Commercial team based in Bridgewater, NJ.

Role Overview Reporting directly to the President, Carvykti BU, this role serves as the BU’s Strategy Execution Lead, driving alignment, execution, and operational effectiveness across Commercial, GMS, Quality, and Medical Affairs. A core responsibility is managing Legend’s strategic alliances—ensuring strong governance, seamless communication, and proactive issue resolution so both organizations deliver on joint CAR‑T objectives. The role also leads BU‑wide engagement and communication, fostering clarity, connection, and cultural cohesion across global teams.

In parallel, it drives capability building, strengthening organizational readiness, talent development, and cross‑functional effectiveness to support Carvykti’s rapid growth and strategic priorities.

Key Responsibilities

Alliance Management: Lead governance of current and future alliances, ensuring transparent communication, shared accountability, and timely escalation. Coordinate joint steering committees, joint working teams, and governance bodies to ensure compliance with collaboration agreements and delivery on shared milestones. , Janssen) and serve as a central connective point between Carvykti BU functional stakeholders and alliance partners.

Proactively identify risks, misalignments, or emerging strategic opportunities within collaborations and drive resolution or acceleration initiatives. Ensure open communication channels across both organizations and consistent partnership health tracking. Engagement Communication: Drive engagement initiatives and forums - town halls, BU business reviews, culture initiatives, leader communications, and cross‑functional alignment sessions.

Serve as a strategic advisor to the BU President on messaging, engagement cadence, and organizational pulse. Design and lead BU‑level internal communications strategy, ensuring clarity, transparency, and alignment from the President through LT‑1 and field/operational teams. Innovation Strategy Acceleration: Partner with BU President LT to shape and drive BU strategic initiatives, including transformation, digital capability scaling, operational innovation, and cross‑functional initiatives.

Monitor industry trends (CAR‑T evolution, regulatory updates, partnership models) and translate insights into BU priorities. Capability Building: Support BU‑wide capability strategy (technical, leadership, and operational), to ensure teams are equipped for current and future needs across Commercial, GMS, Quality, and Medical Affairs. Build mechanisms to measure capability maturity and organizational effectiveness.

Partner with HRBP, OD, and Functional Heads to design learning ecosystems and talent acceleration pathways. The Head, Business Operations and Alliance Mgmt.