Manifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening to unlock tissue-targeted medicines and organism-scale models of living systems. Using proprietary molecular barcoding technology, we screen hundreds of thousands of protein designs simultaneously in living systems, producing in vivo-validated datasets at a scale no one else can match. The datasets power our computational models, which leads to better drug designs, creating a flywheel that gets stronger with every campaign.

Our team of protein engineers, biologists, and computational scientists works across this full stack to pursue programs both internally and with leading pharma companies. Position Manifold Bio is seeking a highly organized and proactive Senior Lab Operations Associate to support the day-to-day operations of our laboratory and facility. Reporting to the Associate Director of Operations, you will serve as a critical operational partner to our scientific teams by coordinating laboratory support activities, managing vendors and service providers, maintaining operational systems and records, and ensuring that routine laboratory operations run efficiently and reliably.

This is a highly visible, hands-on role where your effectiveness will directly impact the productivity of our scientific teams and the reliability of our research infrastructure. You will serve as the primary point of coordination for routine laboratory operations, helping scientists stay focused on advancing research while ensuring the facility, equipment, inventories, vendors, and compliance programs that support their work operate seamlessly in the background. The ideal candidate thrives in a fast-paced environment, enjoys solving problems, and takes pride in building systems that scale.

You are highly organized, detail-oriented, and proactive, with a strong sense of ownership and a willingness to jump into whatever is needed to keep the laboratory running smoothly. Whether coordinating an equipment repair, supporting a new hire's onboarding, managing a vendor visit, or improving an operational process, you approach challenges with urgency, professionalism, and a service-oriented mindset.

Responsibilities

Operational Coordination Own and manage the Lab Operations ticket queue, ensuring timely resolution or escalation of requests Coordinate day-to-day laboratory support activities and operational priorities Facilitate Lab Operations meetings and track follow-up actions to completion Maintain operational documentation, inventories, department records, and laboratory operating procedures Support onboarding and offboarding activities, including workspace setup, laboratory access, equipment coordination, and operational training Own consumable inventory management and replenishment processes to ensure uninterrupted laboratory operations Identify operational improvement opportunities and recommend practical, scalable solutions Scientific Partnership Serve as the primary point of contact for routine operational support requests from scientific staff Partner closely with scientists to identify operational needs and coordinate solutions that minimize disruption to research activities Participate in cross-functional planning and coordination activities Escalate competing priorities, resource constraints, and unresolved operational issues to the Associate Director of Operations Facilities Vendor Coordination Coordinate routine facility maintenance, contractor activities, and service provider visits Own vendor scheduling and preventive maintenance planning for laboratory and facility equipment Coordinate equipment installations, repairs, calibrations, certifications, and service appointments Obtain quotes and coordinate purchasing activities as requested Track facility and infrastructure issues and escalate risks or unresolved concerns appropriately EHS Compliance Coordinate day-to-day EHS activities and support laboratory complia