Senior Director, Head of Search & Evaluation

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.

As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Senior Director, Head of Search Evaluation is a senior leader within the Business Development organization responsible for identifying, assessing, and advancing external innovation opportunities that support Revolution Medicines' portfolio strategy and long-term growth objectives. Working in close partnership with leaders across Research, Development, Commercial, Corporate Strategy, Portfolio Management, and Executive Management, this individual will lead the company's search and evaluation activities across discovery and clinical-stage opportunities.

The role is accountable for developing and maintaining a robust pipeline of external opportunities, driving rigorous opportunity assessments, and providing strategic recommendations that inform portfolio and partnering decisions. The successful candidate will combine deep scientific and business acumen with strong leadership, analytical, and communication skills. This individual will serve as a key connector across the organization, ensuring that external innovation efforts are aligned with corporate strategy, therapeutic area priorities, and emerging opportunities in precision oncology and related fields.

Required Skills, Experience and Education: External Innovation Strategy and Opportunity Identification Lead the company's search and evaluation of external innovation in partnership with senior cross-functional stakeholders. Develop and execute search strategies that align with Revolution Medicines' research, development, and commercial priorities. Oversee all discovery- and clinical-stage search and evaluation activities, ensuring a robust pipeline of external opportunities aligned with portfolio priorities.

Drive proactive opportunity sourcing through engagement with biotechnology companies, academic institutions, investors, entrepreneurs, and other innovation ecosystems. Partner with Portfolio Management, Disease Strategy, Research, and Development leaders to identify areas where external innovation can create strategic value and enhance portfolio competitiveness. Maintain a comprehensive understanding of relevant scientific, clinical, and competitive landscapes to identify emerging opportunities and trends.

Opportunity Assessment and Diligence Leadership Lead cross-functional diligence and opportunity assessments, integrating scientific, clinical, commercial, strategic, operational, and financial perspectives into executive recommendations. Establish clear evaluation frameworks and decision criteria that support consistent and rigorous assessment of external opportunities. Coordinate diligence activities across Research, Clinical Development, Regulatory, Commercial, Finance, Intellectual Property, Legal, and other functions.

Ensure key risks, opportunities, and strategic considerations are thoroughly evaluated and clearly communicated to decision-makers. Develop balanced recommendations regarding prioritization, resource allocation, and partnership strategy. Portfolio and Governance Leadership Establish and maintain scalable frameworks for opportunity evaluation, diligence governance, prioritization, and decision-making.