Senior Director, Global Medical Affairs - GI Oncology

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.

As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Reporting to the GI Tumors Medical Affairs Strategy Lead, the Senior Director, Global Medical Affairs, will be responsible for developing and executing the Global Medical Affairs (GMA) strategy and tactical plans with a focus on launch readiness, launch implementation and life cycle management for an individual asset. The successful candidate will have a proven track record of developing and driving medical strategies with a focus on effectively communicating key scientific data through publications, medical information, medical communications, and congress activities.

The successful candidate will also have experience gathering and analyzing insights through Advisory Boards, Key Opinion Leader (KOL) engagements and interaction with local/regional medical teams and translating those insights into tactics that optimize asset utilization and impact the drug lifecycle. This role requires close collaboration with cross-functional counterparts across Development, Research and Commercial as well as other internal partners, to design and implement a comprehensive medical affairs strategy for assets in the GI space, with focus on PDAC and CRC.

Key Responsibilities

: Develops and executes the GMA strategy and medical objectives including activities related to scientific engagement and communication, evidence generation, internal education, and patient advocacy. Develops and executes a Health Care Professional (HCP) engagement strategy to gather insights to shape internal programs. Acts as the medical representative on cross-functional teams.

Serves as a therapeutic area content expert. Participates in the Global Medical Affairs Team (GMAT) to execute medical strategies, contribute to the operations and oversight of medical activities, and work cross-functionally to support associated pre-launch activities. Supports the execution of routine gap assessments leading to the development/refinement of publication strategy, evidence generation plans, and tactical plan as part of the overall GMA plan.

Provides medical leadership in scientific engagement activities with key external stakeholders through organizing and leading advisory boards, studies investigator interactions, congress activities, and peer-to-peer discussions with the goal of communicating scientific insights to internal teams to drive strategy. Communicates clinical and scientific data to KOLs and other healthcare professionals through presentations, educational programs, and scientific discussions. Represents various medical affairs functions in cross-functional strategy team meetings including Clinical and Safety sub-teams, Global Brand Team, Global Product Team, Patient Advocacy, Market Access, and other cross-functional strategic discussions.

Works closely with the Clinical and MSL teams to provide enrollment, scientific, and engagement support to ensure clinical trials meet study timelines. Partners with RWE strategy and Biomarker/CDx teams on related integrated evidence generation strategies and activities as part of the GMA Plan. Works with the Patient Advocacy and Grants teams to incorporate the patient voice and define external medical education strategies for independent grants, respectively.