Lab Automation Engineer

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development.

As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: We are seeking an Associate Automation Engineer to join our laboratory automation team. The successful candidate will support the day-to-day operation, maintenance, troubleshooting, and optimization of automated laboratory instrumentation and integrated automation systems.

This individual will work closely with scientists, engineers, and cross-functional teams to ensure reliable laboratory operations and support automation-driven workflows. The ideal candidate will have hands-on experience with laboratory automation platforms, instrumentation support, software-driven workflows, equipment validation, and troubleshooting of mechanical systems, along with a strong interest in process improvement and operational efficiency. As a member of the Automation Engineering team, you will contribute to the team with accountability for the following: Develop and maintain automation methods using laboratory control platforms such as Tecan FluentControl, Hamilton Venus, Agilent VWorks, HighRes Cellario Scheduler, and Beckman Coulter Tempo/Echo.

Provide hands-on support, troubleshooting, and maintenance for automated laboratory instrumentation and integrated automation systems to ensure reliable day-to-day operations. Diagnose and resolve complex mechanical, software, and system integration issues to minimize equipment downtime and maintain operational continuity. Perform routine, preventive, and corrective maintenance activities, including equipment upgrades, modifications, and validation support.

Execute installation, testing, and validation activities to verify equipment performance, accuracy, reliability, and laboratory stability. Coordinate issue triage with vendors and external service providers while maintaining accurate equipment records, maintenance logs, and validation documentation. Train end users on laboratory automation systems and contribute to process improvements, operational initiatives, and innovations that enhance laboratory efficiency.

Required Skills, Experience and Education: Bachelor’s degree in engineering, scientific discipline, or a related field. 3+ years of relevant experience including service or support role. Experience with laboratory instrumentation and automation systems.

Good communication and organizational skills. Preferred Skills: Knowledge of discovery chemistry lab workflows including compound management and HTS. Experience troubleshooting liquid handling instruments such as Tecan Fluent or Hamilton STAR.

Experience writing protocols for Tecan Fluent, Hamilton Venus, and Cellario Scheduler. #LI-Hybrid #LI-LN1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in.

Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.