Scientist I, Compound Management

About Us Valo Health is a human-centric, AI-enabled biotechnology company working to make new drugs for patients faster. The company’s Opal Computational Platform transforms drug discovery and development through a unique combination of real-world data, AI, human translational models and predictive chemistry. Our talented team of biologists, chemists and engineers, armed with advanced AI/ML tools, work together to break down traditional R D silos and accelerate the speed and scale of drug discovery and development.

Valo is committed to hiring diverse talent, prioritizing growth and development, fostering an inclusive environment, and creating opportunities to bring together a group of different experiences, backgrounds, and voices to work together. We embrace new ways of learning, solve complex problems and welcome diverse perspectives that can help us advance patient-centric innovation. Valo is headquartered in Lexington, MA, with additional offices in New York, NY and Tel Aviv, Israel.

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About The Role

Valo Health is seeking a Scientist I to join the Compound Management team, supporting the day-to-day operations of compound handling, registration, and distribution across its drug discovery organization. This is a hands-on laboratory role for a detail-oriented, resourceful scientist with strong experience in compound management automation and a continuous improvement mindset. The successful candidate will work cross-functionally with IVP, ADME, chemistry, and DEL technology teams to ensure compounds are accurately tracked, prepared, and delivered to support Valo’s scientific functions.

What You’Ll Do

… Execute compound management workflows including compound registration, weighing, stock solution reformatting, inventory curation, liquid-liquid plate transfers, and archive storage. Partner with IVP, ADME, chemistry, and biology teams to coordinate compound activities and deliver assay-ready plates in support of rapid DMTA cycles and HTS campaigns. Maintain consumable supplies; author and maintain SOPs, protocols, and inventory records to ensure data integrity, accurate audit trails, and operational continuity.

Interface with CROs and vendors for external compound inventories, purchasable compound orders, and shipments; support service contract coordination and vendor troubleshooting. Work with chemistry and DEL technology teams to curate and manage the chemical building block inventory, ensuring accurate registration, stock integrity, and alignment with program needs. Design and enable new plating workflows to support IVP and ADME science teams; troubleshoot automation and software platforms and integrate novel workflows as needs evolve.

Stay current with industry trends in compound management and liquid handling; propose and build the case for adoption of new technologies and workflow improvements. What You Bring... BS in a scientific discipline with 8+ years of relevant laboratory experience, including a minimum of 5 years in compound management.

Resourceful and highly organized, with a detail-oriented approach to planning and executing at the bench; ability to manage multiple priorities concurrently. Experience operating and troubleshooting compound management automation platforms, liquid handling, acoustic dispensation, and periphery devices (tube sorting, 2D barcode scanning). Experience with sample storage systems and integrations with liquid handlers and automation systems.

Liquid handling scripting, workflow scheduling, and software programming are strong pluses; experience with Titian Mosaic and Dotmatics LIMS is a plus. Ability to work independently and cross-functionally with IVP, ADME, and chemistry teams in a collaborative, dynamic environment; strong commitment to inventory control, accurate recordkeeping, and audit readiness. Continuous improvement mindset with a track record of identifying efficiencies and contributing to process development.