Join Us in Shaping the Future of Clinical Research Adams Clinical is a leading clinical trial site network committed to accelerating the development of life-changing medicines. Our mission is simple: deliver uncompromising data quality, safety, and diverse enrollment to advance healthcare. Our vision is to set the gold standard for clinical trial excellence.

We believe our people make the difference. Guided by our core values— Scientific Rigor, Operational Excellence, Commitment to Sponsors and Participants, and Authentic Collaboration —we create an environment where meaningful work drives meaningful change. At Adams Clinical, you’ll find: A culture of respect, transparency, and continuous improvement Opportunities for professional growth and learning A team dedicated to improving lives through innovation and integrity If you’re passionate about making an impact in clinical research and want to be part of a collaborative, mission-driven organization, we’d love to have you on our team.

Job Role We are seeking a Senior Manager, Clinical Operations for a full-time role at our Watertown location. The Senior Manager, Clinical Operations will oversee day-to-day site-level operations and provide leadership across study teams. This individual will be responsible for staff management, operational oversight, regulatory compliance, and ensuring high-quality trial execution that meets both sponsor expectations and business objectives.

Key Responsibilities

: Study Operations and Site Performance Serve as primary point of contact for day-to-day site issues; monitor study activities, enrollment, visit schedules, and site performance metrics for both inpatient and outpatient studies. Support subject recruitment, eligibility assessments, randomization, and oversee study processes including ALCOA-compliant documentation, study trackers, investigational product handling, and ensure proper handling of participant safety events and adverse events (SAE/AESI reporting). Identify operational, regulatory, or safety risks, implement mitigation strategies with senior leadership, and escalate critical issues.

Work closely with the Inpatient Unit Manager and the Associate Director of Inpatient Clinical Operations to support and oversee the conduct and quality of all inpatient studies at the Watertown inpatient facility. Ensure alignment on workflows, study execution, and safety practices within the inpatient unit. Collaborate with Finance to review Clinical Trial Agreement (CTA) invoicing, oversee participant reimbursement processes, and support site-level budget monitoring and forecasting to ensure financial compliance and operational efficiency.

Responsibilities

and track staff involvement across studies. Oversee the recruitment, hiring, and onboarding of key site personnel (PIs, clinicians, nurses, DSMs, CRCs, RAs) and conduct regular team huddles to review study progress. Collaborate with leadership across departments and sites to coordinate resources, streamline processes, and drive operational excellence.

Work closely with the Director and Vice President of Clinical Operations along with leaders of other departments and sites to coordinate resources, streamline processes, and drive operational excellence. This position reports directly to the Director of Clinical Operations. Facilities Oversight Oversee facility and building maintenance, including office services, safety inspections, drug room security, and pest control, while ensuring efficient use of site space and adequate workspaces for staff.

Coordinate calibration of research equipment and support renovation, expansion, and relocation projects. Manage local vendor contracts for study-related services, including laboratories and imaging.