Director, Antibody Discovery

Position Summary: Quotient is seeking a Director or Senior Director of Antibody Discovery. This role will define and lead Quotient’s antibody discovery strategy; leading the delivery of therapeutic antibody projects in addition to Quotient’s antibody drug discovery platform build through the deployment of cutting-edge technologies. e.

candidate genes and potential drug targets) into initiation of drug discovery programs. This role will also involve senior project leadership, steering drug discovery matrix teams from early conception through to key inflection points such as development candidate nomination and IND submission.

Responsibilities

: Provide balanced expert advice on the feasibility of antibody tractable targets and the conception of high-value drug molecules Present antibody discovery strategies to internal R D committees to justify capital commitment in new programs Drive decision making on construct design, format and developability for new antibody programs according to Target Product Profile specifications Independently carry out lead sequence and format optimizations utilizing rational, structure-based and in silico/AI/ML design approaches Drive rapid optimization of novel antibody and protein therapeutics through iterative design, build, test, and learn cycles As a drug discovery project leader, develop efficient and balanced project plans for one or more biologic drug discovery programs and lead a cross-functional team to execute through lead generation, development candidate nomination and IND submission Model best matrix leadership behaviours and support an emphasis on enterprise leadership across the company Identify, select, and manage external CROs/vendors, consultants, and academic collaborators to deliver a virtual/outsourced state-of-the-art drug antibody discovery platform for the identification of high-quality mAb molecules at pace Build and maintain networks of external experts to pressure-test hypotheses and refine strategies Serve as a specialist antibody discovery expert within Quotient’s drug discovery team and across the company.

Qualifications

: Essential Proven experience advancing protein therapeutics through drug discovery phases to development.