Vendor & Budget Manager, Clinical Operations

Who Are We? Our company is based on the science of our founder, Stanley Qi, one of the original CRISPR co-inventors who then furthered the technology so that DNA does not need to be cut to accomplish gene regulation. Instead, we regulate the epigenome to suppress and activate multiple genes simultaneously.

We are further evolving the platform and leveraging its strengths to address unmet medical needs. We are looking for exceptional team members who want an active role in building a rapidly growing biotech. Position: Vendor Budget Manager, Clinical Operations Location: South San Francisco, CA Opportunity : Epicrispr Biotechnologies is seeking a Vendor and Budget Manager to join our growing Clinical Operations team.

This role will play a critical part in overseeing vendor relationships, contracts, and budgets to support the successful execution of our clinical programs. This is a highly cross-functional role partnering closely with Clinical Operations, Finance, Legal, and external vendors to ensure studies are executed efficiently and in alignment with timelines, scope, and budget.

Responsibilities

: Primary administrative point of contact for vendor coordination and communications, ensuring alignment with study priorities defined by Clinical Operations.

Requirements

defined by Clinical Operations. Manage all existing clinical vendors, requiring contract oversight and coordination with legal and internal teams, budget and PO oversight alongside internal finance and accounting, while partnering with the CTM and other Clinical Operations team members to ensure vendor deliverables align with study needs. Oversee site master budgets and ensure alignment with protocol updates, in coordination with CTM and Clin Ops priorities.

Approve vendor invoices and budgets, including pass throughs from CRO, ensuring consistency with agreed scopes of work and escalation of discrepancies as needed. Support CMO, CTM, and Clinical Operations Lead with review of budget reporting from CRO alongside finance and accounting team. Track vendor performance, deliverables, contractual obligations, and escalate risks or delays to the Clinical Operations Lead.

: Bachelor’s degree in life sciences, business, or related field required Typically 5+ years of experience in clinical operations, vendor management, or clinical trial management within biotech, pharma, or CRO environments Strong understanding of clinical trial processes, vendor oversight, and GCP/ICH guidelines Experience managing contracts, budgets, and vendor relationships across multiple studies or programs Familiarity with CRO models, pass-through costs, and financial tracking processes Excellent organizational and project management skills with strong attention to detail Strong communication and stakeholder management skills, with the ability to work cross-functionally Ability to manage multiple priorities in a fast-paced, evolving environment Proficiency with clinical systems (e.g., CTMS, eTMF) and financial tracking tools preferred

Compensation

: The salary range for this position is $135,000 to $145,000 USD annually. This salary range is an estimate, and the actual salary may vary based on various factors, including, without limitation, individual education, experience, tenure, skills, and abilities, as well as internal equity and alignment with market data, including potential adjustments for geographic location. Epicrispr Biotechnologies is an early-stage biotechnology company developing a novel technology platform that can provide safe and persistent control of targeted gene regulation.

Our proprietary platform represents an entirely new class of therapeutics that can be leveraged to treat severe disease across numerous therapeutic areas, including complex diseases impacted by multiple genes.