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Boku Inc. — Cambridge, Cambridgeshire
Position Summary: Quotient is seeking a Flow Cytometry and Fluorescence Activated Cell Sorting Senior Research Associate to join our High Throughput Platform team. The primary focus of this role is the isolation and sorting of cells and nuclei from human tissues to support downstream somatic genomics workflows, including DNA extraction and sequencing library preparation to support detection of disease relevant somatic variants. The successful candidate will work closely with our Flow Cytometry and Automation platforms to refine our processes and scale our Flow Cytometry operations.
In addition, this position will provide growth opportunities to learn and contribute to disease projects across our histology and/or molecular workflows. The ideal candidate will thrive in a fast-paced, cross-functional environment, supporting delivery across prioritized workstreams with agility, positivity, and a proactive mindset. They will demonstrate initiative in solving problems, raising concerns, and driving improvements, while remaining committed to continuous learning, open feedback, and working beyond their comfort zone.
Responsibilities
: Conduct cell sorting experiments to isolate specific cell/nuclei populations, with high purity and viability. Operate and troubleshoot flow cytometry and cell sorting equipment Support the design and optimization of tissue dissociation and cell/nuclei isolation methods to meet project goals Perform the preparation and dissociation of human tissues and cells Perform nucleic acid extraction and sequencing library preparation. Work collaboratively with other team members across various functional areas.
Qualifications
: Essential BSc or MSc degree in a biologically relevant field 3+ years experience of flow cytometry (optimizing staining conditions, Improving signal/noise, panel optimization, reagent evaluation).