Iovance Biotherapeutics aims to be the global leader in innovating, developing and delivering tumor infiltrating lymphocyte (TIL) therapy for people with cancer. We are pioneering a transformational approach to treating cancer by harnessing the ability of the human immune system to recognize and attack diverse cancer cells in each patient. The Iovance TIL platform has demonstrated promising clinical data across multiple solid tumors.

We are committed to continuous innovation in cell therapy, including gene-edited cell therapy, which may be a promising option for patients with cancer. Overview The Assistant Corporate Controller is a senior finance leader responsible for the overall management of the Company’s accounting operations, financial reporting, and internal controls. This role partners closely with executive leadership and cross-functional teams to ensure financial integrity, SEC and GAAP compliance, and scalable accounting infrastructure at a commercial-stage cell therapy company.

The Assistant Controller plays a key role in supporting Iovance’s mission — advancing cell therapy for patients with cancer — by building robust financial processes, leading system implementations, and driving governance through SOX compliance and disclosure committee participation.

Responsibilities

Financial Close Reporting Oversee monthly/quarterly close process for general ledger accounts and all related activities for the production of financial statements and reports. Ensure integrity of the Company’s accounting systems, including interfaces from payroll, equity, and expense management systems to the general ledger. Prepare monthly/quarterly financial review decks; synthesize financial results and key metrics for executive and board-level audiences.

Analyze and interpret financial statements — balance sheets, income statements, and cash flow statements — to support management decision-making. SEC Reporting Disclosure Review and manage SEC reporting, including 10-K, 10-Q, and proxy statements, ensuring accuracy, completeness, and compliance with applicable rules and regulations. Partner cross-functionally with Legal, Investor Relations, and business teams to align on disclosure language and ensure consistent, transparent external communications.

Co-chair the Disclosure Committee to oversee preparation and review of financial results and non-financial metrics prior to external publication. S. GAAP.

Review clinical trial accruals and other biopharma-specific accounting matters. Monitor evolving accounting standards and assess their impact on the Company’s financial statements and disclosures. Partner with the Director of Tax on the review of the tax provision, including tie-out of numbers, schedules, and underlying assumptions to ensure alignment with the financial statements.

SOX Compliance Internal Controls Establish, maintain, and monitor a robust SOX-compliant internal control framework across accounting and finance processes. Lead the design and implementation of SOX controls over new processes and continuously seek enhancements to existing controls, including risk assessment, documentation, and remediation. Partner with internal and external auditors to support SOX testing, audit readiness, and timely resolution of findings.

Systems Implementation Process Optimization Lead cross-functional implementation and optimization of Procure-to-Pay (P2P) platforms integrated with ERP (NetSuite), ensuring scalable, efficient, and well-controlled processes. Establish SOX-compliant internal controls across P2P processes as part of system rollout, including policy development, segregation of duties, and user access governance. Drive continuous improvement of accounting systems and processes to support the Company’s growth and operational scale.