Accounting Manager, R&D (Non-Clinical)

About Summit: Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality.

Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people. Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence. Summit’s team is inspired to touch and help change lives through Summit’s clinical studies in the field of oncology.

Summit has multiple global Phase 3 clinical studies, including: Non-small Cell Lung Cancer (NSCLC) HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI. HARMONi-3: Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC. HARMONi-7: Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.

Colorectal Cancer (CRC) HARMONi-GI3: Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy. Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.

, Europe, China). This role is central to ensuring R D expenses are accurately accrued, analyzed, and supported, with close collaboration across vendors, internal project managers, and cross functional teams. This position requires a hands-on accounting leader who goes beyond transactional accounting to critically assess R D activity and ensure accruals accurately represent the business.

, Europe, and China, this role plays a key part in supporting global audits and statutory financial reporting in a dynamic, high growth environment.

Responsibilities

: Own the end-to-end R D accrual and expense accounting process for nonclinical activities, ensuring costs are accurately captured and reflect underlying business activity Prepare and review monthly journal entries and account reconciliations, exercising judgment to assess completeness, accuracy, and overall reasonableness Partner closely with vendors, internal project managers, and cross functional R D teams to obtain data, validate assumptions, and support accrual calculations Support R D cost areas including manufacturing, patient safety, biostatistics, CMC, supply chain, and non-trial clinical operations expenses Play a key role in the monthly close process, contributing to continuous improvement, documentation, and close efficiency Support global audits and statutory financial statements across the U.S., UK, and Switzerland by preparing schedules, analyses, and audit support Contribute to internal controls, SOX readiness, and accounting process development as the company continues to scale Ad-hoc tasks as assigned All other duties as assigned Experience, Education and Specialized Knowledge and Skills: Bachelor’s degree in Accounting, Finance, Business, re