Senior Brand Director, Obexelimab

Zenas is a clinical-stage global biopharmaceutical company committed to becoming a leader in the development and commercialization of transformative therapies for patients with autoimmune diseases.

Benefits

to patients living with autoimmune diseases. Zenas is advancing two late-stage, potential franchise molecules, obexelimab and orelabrutinib. Obexelimab, Zenas’ lead product candidate, is a bifunctional monoclonal antibody designed to bind both CD19 and FcγRIIb, which are broadly present across B cell lineage, to inhibit the activity of cells that are implicated in many autoimmune diseases without depleting them.

We believe that obexelimab’s unique mechanism of action and self-administered, subcutaneous injection regimen may broadly and effectively address the pathogenic role of B cell lineage in chronic autoimmune disease. Orelabrutinib is a potentially best-in-class, highly selective CNS-penetrant, oral, small molecule Bruton’s Tyrosine Kinase (BTK) inhibitor with the potential to address compartmentalized inflammation and disease progression in Multiple Sclerosis (MS). Zenas’ earlier stage programs include ZB021, a clinical-stage, potentially best-in-class, oral, IL-17AA/AF inhibitor; ZB022, a preclinical, potentially best-in-class, oral, brain-penetrant, TYK2 inhibitor; and ZB014, a preclinical half-life extended anti-CD-19 and FcγRIIb monoclonal antibody.

We are seeking top talent who share our commitment to patients and have a track record of success in acquiring, developing and commercializing products across the globe. Our colleagues have an opportunity to engage in a fast-paced learning environment and experience individual and organizational success as we work towards becoming a global immunology and autoimmune disease leader, while living our values of Transparency, Relationships, Urgency, Excellence and Innovation – TRUE Innovation ! Position Summary: Zenas is seeking a seasoned, dynamic commercial marketing leader with deep US market understanding and experience in immunology, inflammation and/or rare disease to serve as the marketing lead for obexelimab’s first anticipated commercial indication in IgG4-Related Disease (IgG4-RD), setting the strategic direction for brand positioning, messaging, customer segmentation across all audiences, market development, launch readiness and commercial execution.

Reporting to the VP, Head of Marketing, the Senior Brand Director for obexelimab in IgG4-RD will actively participate across the brand’s key workstreams and serve as the marketing voice on the Integrated Brand Launch Team. The role requires a senior marketer with strong executional acumen, the credibility to represent marketing’s perspective across functions, and the ability to translate insight into compelling messages and high-quality launch assets.

Key Responsibilities

: Brand Strategy Launch Readiness Participate as the Marketing lead in the brand strategy for obexelimab in IgG4-RD across all customer audiences, including product positioning, messaging, market differentiation and core strategic choices — bringing the marketing perspective and ensuring marketing activities are aligned with brand strategy. Represent the Marketing team on the Obexelimab Integrated Brand Launch Team, collaborating in strategic alignment across brand, launch and cross-functional workstreams. Contribute to launch-readiness planning by owning marketing milestones, driving execution of marketing activities, and ensuring alignment with brand strategy and commercial investment priorities.

Translate market research, advisory board feedback, competitive intelligence and field insights into actionable brand strategies and tactical plans across customer segments.