About Us Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world. It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve. , Kardigan’s co-founders have reunited after leading MyoKardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020.

We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients. At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals. Driven by patients and their families , we are deeply committed to improving the lives of patients and prioritizing their needs above all else.

We believe in being authentic —leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an eagerness to learn , we encourage the highest levels of curiosity and are open to changing our minds. We are committed to winning as a team with urgency, excellence, and intention, and support each other no matter what role we play or where we sit.

Lastly, we strive to enable the impossible because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries. These values are the foundation of our work, empowering us to make a real difference, every day.

Position Title: Director, Medical Science Liaison / Regional Medical Lead – Cardiovascular Department: Medical Affairs Reports To: Head of Medical Affairs (ad interim – will report to National Director of Field Medical) Location: Field-Based (Regional) Job Overview The Director, Medical Science Liaison (MSL) / Regional Medical Lead (RML) serves as a field-based scientific leader responsible for advancing the medical strategy within a defined region.

Responsibilities

with regional leadership oversight, strategic execution, and cross-functional collaboration to support cardiovascular assets across approved products and pipeline programs. S. medical strategy.

Scientific Engagement KOL Development (MSL Function) Develop and maintain strategic peer-to-peer relationships with leading cardiologists, heart failure specialists, interventionalists, and academic researchers. Conduct high-level scientific exchange regarding disease state, mechanism of action, clinical trial data, real-world evidence, and emerging pipeline assets. Present and interpret complex cardiovascular clinical data (Preclinical research, Phase I–IV , biomarker data).

Identify unmet needs and evolving trends within cardiovascular treatment paradigms. Support medical congresses (ACC, AHA, ESC, HFSA) through scientific engagement and insight capture. Facilitate investigator-initiated studies (IIS) and research collaborations.

As a Regional Medical Lead, additional

include: Regional Strategy Execution Translate national/global cardiovascular medical strategy into actionable regional plans. Prioritize KOL engagement and resource allocation based on regional impact. Identify high-value centers for clinical development and research partnerships.

Drive alignment between medical objectives and regional market dynamics.